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KMID : 1103720080580010021
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Journal of the Korean Society of Radiology
2008 Volume.58 No. 1 p.21 ~ p.28
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Long-term Follow-up Sonography of Benign Cystic Thyroid Modules after a Percutaneous Ethanol Injection: The Incidence of Malignancy-mimicking Nodules
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Park Ji-Sung
Choi Seok-Jin
Eun Choong-ki
Kim Dong-Wook
Rho Myung-Ho
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Abstract
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Purpose: To evaluate the incidence of malignancy-mimicking sclerosed thyroid nodules, from long-term follow-up ultrasonography (US) after an US-guided percutaneous ethanol injection (PEI).
Materials and Methods: We examined 86 benign cystic thyroid nodules from 80 patients. The nodules were classified into two groups based on whether an aspiration (Group A, n=26) or non-aspiration (Group B, n=60) of infused ethanol was performed. The final follow-up US over 12 months was performed in all patients.
Results: Of the 86 nodules, the cystic portion of 82 (95.3%) cases, from 76 patients, completely disappeared subsequent to the first follow-up US (Group A, n=24, Group B, n=58) (Chi-square test, p>0.05). Moreover, 46 sclerosed thyroid nodules showed two or more of the ’five sonographic criteria’ upon a follow-up US (Group A, n=13, 50.0%, Group B, n=32, 53.3%). A higher ratio of the cystic portion of the nodules was associated with a higher incidence of the ’five sonographic criteria’ for malignancies detected via a follow-up US (p<0.01; Student’s t-test).
Conclusion: For the long-term follow-up US, the ’five sonographic criteria’ were observed in half the patients who received US-guided PEI. Also, by acknowledging the possibility that sonographic findings mimic a malignancy, since the sclerosed thyroid nodule, patients may avoid an unnecessary biopsy.
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KEYWORD
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Thyroid nodule, Ethanol sclerotherapy, Ultrasonography, Sclerotherapy
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